I think it will tell you on the packaging that it must not be administered to lambs under 3 weeks old. I only vaccinate lambs this young if they are orphans and have been having formula milk after the first 24 hours of colostrum or replacer. Otherwise, if they've been on their mums all along, I don't vaccinate at all if they will be fattened before the first winter. Keeping ewe lambs get vaccinated mid-winter, or late winter if they are being tupped in their first year.