[sheeponthebrain]

I left the bottle of vecoxan in the cattle shed this last night, only to find it partly frozen this morning.  my question is.  Will this mean it's ruined?  or will it have a reduced efficacy?

[harmony]

The info on NOAH says protect from frost so I think it will have been affected.

[pharnorth]

It's quite unusual for a pharmaceutical product to have a do not freeze instruction so the manufacturer will have a specific reason for this. Possibly directly on efficacy of the active ingredient of could be excipient matrix related. Either way it certainly suggests the product won't do what you need.