Ours were isolated, given a course of pen&strep in case of secondary infection. Mouths sprayed with alamycin spray however after about a week we stopped doing this and let the virus just run its course. Orf paste is quite good but difficult to apply. It didn't affect our tame lambs from drinking, in fact the 3 biggest lambs were the ones that got the virus. Vaccinated the other 4 in the pen with scabivax. In the end we just kept handling to a minimum, made sure they were drinking ok and left them be. Make sure you wear gloves!