And I will share some first hand experiences too.
When I first went up north, I was on a farm with 530 breeding ewes. We used Crovect on the 60 hoggs against keds and lice, and on the 1000+ lambs against flystrike. (In general we didn't find the ewes needed any treatment.)
In treating 1000+ lambs in a day, Crovect ate through my overtrousers (good ones - Flexothane), and even though we did the work outside, the fumes affected my lungs, and the amount in the air that landed on my bare arms I think also had an effect. Anyway, I was wobbly and had breathing problems afterwards, which cleared up quickly, but I found after that that I was sensitised to the stuff and couldn't use it without full protective gear, including full face mask (like a welder's mask.) It eats through latex gloves and Flexothane overtrousers so I also had to be very careful about how much I got on those things and go wash them off periodically.
If I got a whiff of it, or a splash on my skin, I would get an immediate reaction, akin to asthma, with streaming eyes and itchiness.
Once I had moved to the hill farm with ex-BH I was able to leave the Crovecting to him, and although I would help in the pens I made sure to be upwind of him when he was spraying. We didn't spray all the lambs' fleeces every year, just the groups and body parts ex-BH judged to be at risk (if any), but we did do heads of all the lambs in certain fields as head flies were a problem on that farm.
My last year there, we had had my sheep in for Crovect against head flies, as they were being particularly troublesome in the riverside pastures where my sheep were, and I had quite a few lambs with horns, which always increases the risk. As usual, ex-BH did the spraying for me.
The next day, one of my lambs was completely paralysed, unable to get up at all. We got her up to the farmstead and cared for her in a stable. Two days later, another lamb was wobbly, and the day after that I could catch him very easily, so I brought him up too.
Something made me look at the Crovect gun. It was set for a full body adult sheep dose. Somehow, the normally very careful ex-BH had not adjusted it down to the very small dose we would normally use for doing lambs' heads. So they had got a huge overdose of Crovect, and the symptoms were neurological.
I worked with the two of them for many days, massaging them and putting them through the motions of walking. After a couple of weeks they could wobble across the stable, and another couple of weeks they could go out into the small pet lamb pen for some sun and grass during the day, and come back to the nearby stable at night.
Then one day we were out, away from the farm, and there was an unexpected very wintry shower. (It was summer, but this was north Cumbria.) When we got back, I found the wether lamb paralysed again in the middle of the pen. The ewe lamb had gone into the shelter and was fine, but for some reason the wether hadn't, and the physiological shock had sent him back to how he was at the beginning.
By the time my move was imminent, the wether was still pretty wobbly but able to get about in the area around the farmstead. The gimmer was not 100% but I think you wouldn't have noticed a wobble if you hadn't known her history.
Well, the wether wasn't fit for market yet, and no way would he manage the trip to Cornwall. He had fought so hard to get better, twice, and he had a nice fleece, so I found him a forever home in a felter's flock in Co Durham and drove him and his mum (who was going to the same home) - very steadily! - across myself.
The ewe lamb came with me to Cornwall, and both are still alive and no apparent long-lasting effects.
And I have found that I no longer seem to be sensitised to it myself, either. We do use a very small amount on some of the lambs here, and I have gradually dispensed with the mask and gloves when I do them, having found that just doing a very few hasn't caused me much in the way of ill-effects.
And one final story. When I was on the upland farm with BH, I was given a fleece by a local farmer whose mum was a spinner, and who knew I would like their Jacob x Texel fleeces and picked me out one of the best. I split the fleece with another local spinner, and did a quick spin with some of my half. That evening I was very short of breath and felt weird. I had a thought and rang the farmer to ask if the sheep had been Crovected, and yes, it had, about a month or six weeks earlier he thought.
I washed the fleece then (I often don't wash fleece before spinning, if it's clean, just give it an overnight soak in cold water and let it dry.) Once it had had a good wash, I didn't have any reaction to spinning it - although I have to say, I never did long sessions with that particular fleece!