As I understand it, if vaccination had been an option in the 2001 F&M outbreak stock on the Breeds at Risk register would have been offered it before commercial flocks. There are lots of those, after all. DEFRA understands that genetic diversity is crucial to livestock health and may be vital to feeding the planet in the future. Native sheep breeds, for example, are routinely finished off grass whereas Continental breeds may struggle to do so, particularly in bad weather. The Merino, for example, was used to improve the fleece of the Southdown in the late 1700's but couldn't cope with the British weather.