Never had at home but as I work in HR, regularly get people wanting a job.
For me it depends on the email, if it is addressed appropriately, has well worded content and has been signed by a name I would just respond saying thanks but no opportunities at present. You can usually tell a dodgy one a mile away, the English is normally terrible and there is very little wording or too much that is not relevant. If the CV is a PDF it is normally harmless, most office docs are ok and your virus checking should pick up on bad ones. You never want to open a zip file though as those are most likely to be viruses and never click on hyperlinks.