I got this from the Keepers nursery website about the root stocks they use for Medlar (clearly Mesiplus is not very informative - I've never heard of it before either so might have a quick google later):
Rootstocks
Fruit trees are propagated onto rootstocks. The rootstock is the most important factor in determining the vigour and eventual size of the tree. The choice of rootstock is therefore very important as it will determine the suitability of the tree for the position and the form in which you intend to grow it. Please find below a list of rootstocks and their characteristics.
Medlar: Quince C (Dwarfing )
Requirements Good fertile soil. Ground should be clear of weeds and grass. Stake for at least the first 5 years and preferably permanently.
Mature height 8-10ft (2.4-3m)
Spread 9ft (2.7m)
Planting distance 9ft (2.7m) apart, 12ft (3.6m) between rows
Mature yield
Bearing age 3/4 years
Suitable forms Bush, pyramid, centre leader, cordon, espalier
Medlar: Mespilus ()
Requirements
Mature height
Spread
Planting distance
Mature yield
Bearing age
Suitable forms
Medlar: Quince A (Semi-dwarfing )
Requirements Suitable for a wide range of soils including relatively poor soils. Stake for the first 5 years.
Mature height 10-12ft (3-3.6m )
Spread 12ft (3.6m)
Planting distance 12ft (3.6m) apart, 15ft (4.5m) between rows
Mature yield
Bearing age 4/5 years
Suitable forms Suitable Forms: Half standard, bush, cordon, espalier, container
Medlar: Pyrodwarf (Semi-vigorous )
Requirements A new relatively dwarfing pear rootstock. Can be used for most soil conditions including relatively poor soil and grassed orchards. Stake for the first 5 years.
Mature height Ove 15ft (4.5m)
Spread 15ft (4.5m)
Planting distance 15ft (4.5m) apart, 20ft (6m) between rows
Mature yield
Bearing age 4/5 years
Suitable forms Half Standard
Medlar: Pyrus (Very vigorous )
Requirements Suitable for a wide range of soils including poor soils and grassed orchards. Staking preferable for the first 3 years.
Mature height Over 20ft (6m)
Spread 15ft (4.5m)
Planting distance 20ft (6m) apart, 25ft (7.5m) between rows
Mature yield
Bearing age 5/6 years
Suitable forms Standard
Medlar: Crataegus (Semi-dwarfing )
Requirements Hawthorn (Crataegus monogyna) is commonly used as a rootstock for medlars. Suitable for a wide range of soils including grassed orchards and relatively poor soils. Stake for the first 5 years.
Mature height 10-12ft (3-3.6m )
Spread 15ft (4.5m)
Planting distance 15ft (4.5m) apart, 20ft (6.5m) between rows
Mature yield
Bearing age 3/4 years
Suitable forms Bush, half standard
I guess your decision should be based on what root stocks you're using for the apples and trying to match the sizes if possible (although Medlar is slow growing so you might want a slightly more vigorous root stock for the Medlar).